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Prostate Specific Antigen, Total with Reflex to Free PSA (Includes Free Percentage)
Ordering Recommendation
Acceptable initial test for prostate cancer screening. Preferred test is Prostate Specific Antigen, Total (0070121) in conjunction with digital rectal exam (DRE). May be useful in distinguishing cancer from benign conditions in patients with mildly elevated total PSA and negative DRE.
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST). Also acceptable: Green (lithium heparin), Lavender (K2EDTA), or pink (K2EDTA).
Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Frozen.
Grossly hemolyzed specimens. Vaginal washings.
After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 3 months
Methodology
Quantitative Electrochemiluminescent Immunoassay (ECLIA)
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
Refer to report.
| Test Number |
Components |
Reference Interval |
|---|---|---|
| Prostate Specific Antigen, Reflex | 0.0-4.0 ng/mL | |
| Prostate Specific Antigen, Free, Reflex | By report | |
| Prostate Specific Antigen-Pct Free, Rflx | By report |
Interpretive Data
FDA
Note
If PSA Total is between 3.0-10.0 ng/mL, then Free PSA testing will be added. Additional charges apply.
The Free PSA percentage is calculated using results of the Total and Free PSA tests.
Hotline History
CPT Codes
84153; if reflexed, add 84154
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0080286 | Prostate Specific Antigen, Reflex | 2857-1 |
| 0080287 | Prostate Specific Antigen, Free, Reflex | 10886-0 |
| 0080288 | Prostate Specific Antigen-Pct Free, Rflx | 12841-3 |
Aliases
- Free PSA
- Free Ratio Reflex
- PSA Free/Total Ratio
- PSA ratio
- PSA Total
- PSA Total and Free
- Total PSA
